Urinary incontinences in adults summary
Order ID 53563633773 Type Essay Writer Level Masters Style APA Sources/References 4 Perfect Number of Pages to Order 5-10 Pages
1. Reflect on the individuals you have cared for with continence difficulties and list the causes of urinary incontinence.
2. Outline, in some detail, the role of the neurotransmitter acetylcholine in producing a bladder contraction.
3. Consider how interference with the neurotransmitter may affect bladder control.
4. Drawing on your knowledge of pharmacodynamics (see Chapter 2), what is meant by an antagonist drug?
5. With reference to your knowledge of pharmacokinetics, what advantages might the transdermal patch of oxybutynin have over the oral form in promoting patient adherence? (See Chapter 2)
6. Some of the antimuscarinics can cross the bloodbrain barrier. What are the properties of a drug that would make them more likely to cross the bloodbrain barrier?
7. Some of the antimuscarinic agents are metabolised by the cytochrome P450 enzymes. Drawing on your knowledge of these important metabolising enzymes, explain the effect of the cytochrome P450 enzymes (see Chapter 1).
8. Bearing in mind Lorraines identification of the most bothersome urinary incontinence symptom, what would be your choice of first-line management for her?
9. Oxybutynin is an antimuscarinic. With reference to their pharmacological properties, describe how antimuscarinics can lead to the side effects of dry mouth and constipation.
10. In view of Lorraines expressed wish to try pharmacological treatment for the urgency and urge incontinence, what will your prescribing decision be?
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